To understand the contribution of resident brain macrophages/microglia in our glioma model, we performed Iba1 immunostaining (Appendix Fig S4A) and noticed that Iba1‐positive cells were preferentially localized at the tumor margin and not, in contrast to the F4/80‐positive bone marrow‐derived macrophages (Appendix Fig S4B) in the tumor core (Appendix Fig S4C). Here, AIF1 is linked to neoplasm.