KCNN4 and stroke disorder: As shown in Fig. 2a–f, the infarct area measurements by TTC staining in pMCAO brains indicated that infarct volumes in KCa3.1−/− mice was smaller than those in WT mice, and infarct areas in KCa3.1−/− mice were significantly reduced by 19% at 6 h after pMCAO compared with those in WT mice (p < 0.05, Fig. 2c, d) but there was no significant difference in infarct measurement at 3 h (p = 0.3085, Fig. 2a, b) and 24 h after stroke (p = 0.0951, Fig. 2e, f).