Furthermore, SFRP4 protein levels in EAT were significantly higher in CAD patients than in non-CAD patients (9214.5 vs 5844, P = 0.021), while SFRP4 protein expression in SAT was not different between patients with or without CAD (13,874.5 vs 9883, P = 0.105). Here, SFRP4 is linked to coronary artery disorder.