ADIPOQ and colorectal adenoma: Some cross-sectional as well as meta-analysis studies suggest that low serum adiponectin levels are related to an increased risk of colorectal adenoma [122,123,124], whereas Ochs-Balcom et al. reported no correlation between serum adiponectin levels and an increased risk of colorectal and adenoma in Caucasian and African-American male subjects [125].