Further, Ronchi et al. reported unchanged serum adiponectin levels between patients with active acromegaly and controls [75]; moreover, they found no correlation between adiponectin expression and several metabolic (BMI, waist circumference, and insulin resistance) and/or cardiovascular factors (lipid profile and blood hypertension) in acromegalic patients [75]. The gene discussed is ADIPOQ; the disease is Insulin resistance.