KL and neoplasm: In vivo studies performed in MCF-7/ADR tumor bearing mice showed that higher DOX internalization was seen in HA-MDSOX-KLA treated mice compared to HA-MSDOX and free DOX dosed mice as shown in Figure 3F. Apoptosis and maximum number of non-dividing cells were observed in mice treated with HA-MSDOX-KLA compared to the other groups.