Also, the overexpression of miR-34a significantly inhibited the migratory and invasive potential of esophageal squamous cell carcinoma (ESCC) cells via inhibition of FNDC3B (Fibronectin Type III Domain Containing 3B), MMP2 (matrix metalloproteinase-2) and MMP9 expression levels [25]. This evidence concerns the gene FNDC3B and esophageal squamous cell carcinoma.