In the whole MEN1-positive cohort, the rate of mutations in exon 2 was significantly higher (P = 0.03) in patients with pituitary adenomas than in those with other MEN1-related tumors, whereas the rate of mutations in exon 9 was significantly lower (P = 0.02) in patients without pituitary tumors (Table 4). The gene discussed is MEN1; the disease is pituitary gland adenoma.