In European populations, an association with HLA-B*08 in early onset MG (EOMG, onset < 40 years) have been shown [14, 16], while the strongest HLA risk allele in late onset MG (LOMG, onset >60 years) is DRB1*15:01 allele [16, 17]. The gene discussed is HLA-B; the disease is myasthenia gravis.