GW Kim, JE Lin, AE Snook, A Aing, DJ Merlino, P Li, SA Waldman: Calorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesity.Nutr Diabetes 2016, 23;6:e211. The gene discussed is GUCA2B; the disease is obesity due to melanocortin 4 receptor deficiency.