This virolysis of pancreatic cells may be supported by (1) the inherent susceptibility of pancreatic tissue to influenza virus23 and (2) by the fact that PANC-1 as well as 90% of pancreatic cancers have a KRAS gene mutation,27 leading to a suppression of the antiviral PKR pathway. This evidence concerns the gene EIF2AK2 and familial pancreatic carcinoma.