CXCR3 and acute respiratory distress syndrome: How these CD8+ T cells exactly play a role in the MA-ARDS pathogenesis is still under investigation, but the expression of CXCL10 in the lungs and CXCR3 on the CD8+ T cells suggest that these cytotoxic cells are recruited to the lungs in experimental MA-ARDS as in ECM (Van den Steen et al., 2010; Deroost et al., 2013).