IDH1 and neoplasm: So far, studies have found a strong association of IDH canonical mutations and ATRX mutation (45, 46), whereas cooccurrence of 1p/19q codeletion and ATRX loss have been nearly non-existent; enabling neuropathologists to be able to make determine whether a tumor is of astrocytic or oligodendrocytic lineage without requiring both studies (8, 45).