FANCA and head and neck squamous cell carcinoma: FANCM mutations significantly correlated with increased somatic mutational frequency in the complete HNSCC cohort (mean age was 60.9 +/− 12.4 years; based on personal correspondence with authors), whereas, FANCA had a similar correlation with the frequency of somatic mutations, but specific in cases defined as younger age (mean age was 46.3 +/− 7.0 years) of onset (no indication regarding HPV status; [146]).