DIAPH1 and infection: Upon infection with Flock house virus or the DNA virus Autographa californica multicapsid nucleopolyhedrovirus, the expression of reaper and head involution defective (hid), the products of which antagonize DIAP1, was significantly increased in a manner mediated by the transcription control regions of the two genes, namely, a p53-bound sequence and sequence named the irradiation-responsive enhancer region (71).