Compared with HCs, patients with CHC had also higher proportions of Th17 cells either circulating (1.56 vs. 0.96%) or infiltrating the liver (16.08 vs. 0.82/hpf), associated with higher serum IL-17 levels (84.86 vs. 60.52 pg/mL) (42). The gene discussed is IL17A; the disease is cryohydrocytosis.