However, GTEx analysis of the human transcriptome indicates that EGOT is preferentially expressed in the breast and vagina, pancreas, pituitary and kidney cortex, while TCGA analysis shows that EGOT is upregulated in liver, lung and thyroid carcinomas and downregulated in prostate, breast and kidney tumors, where low levels correlate with poor prognosis (Lonsdale et al., 2013; Li J. et al., 2015). The gene discussed is EGOT; the disease is thyroid gland carcinoma.