ACHE and Alzheimer disease: In AD therefore, cell death could be attributable to this non-hydrolytic action (Greenfield and Vaux, 2002; Greenfield, 2013; Garcia-Ratés et al., 2016), more specifically via a 14mer peptide cleaved from the AChE C-terminus and included within a more stable, larger peptide, T30 (Greenfield and Vaux, 2002).