GPT and dengue disease: In addition to clinical features previously described in DENV infections,13,15 we observed significantly higher frequency of vomiting, retro-orbital pain, hepatomegaly and elevated AST/ALT in the dengue population (versus nondengue), which are not commonly reported.12 Some of these clinical manifestations (rash, bleeding, abdominal pain, hepatomegaly, thrombocytopenia, and elevated AST/ALT) were more common in severe DENV infections (versus DF).