Of these, 340 were upregulated in CML cells (Fig. 2B) ‐including genes like GAS2, RXFP1, MAMDC2, PIEZO2, HPGDS, CPA3, DPP4, CACNA1D, (Table S1)‐ and 244 were downregulated (Fig. 2B), as compared to normal cells, including ABI3BP, EMP1, PLAG1, PCDH9, ETV3, SELP, IL12RB2, and ID1 (Table S1). The gene discussed is PIEZO2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.