Of these, 340 were upregulated in CML cells (Fig. 2B) ‐including genes like GAS2, RXFP1, MAMDC2, PIEZO2, HPGDS, CPA3, DPP4, CACNA1D, (Table S1)‐ and 244 were downregulated (Fig. 2B), as compared to normal cells, including ABI3BP, EMP1, PLAG1, PCDH9, ETV3, SELP, IL12RB2, and ID1 (Table S1). This evidence concerns the gene CACNA1D and chronic myelogenous leukemia, BCR-ABL1 positive.