Furthermore, according to the 2016 ASAS-EULAR management recommendations of axial spondyloarthritis for the therapeutic efficacy of different TNF blockades on extra-articular manifestations, mAbs are effective in the treatment of IBD and in preventing the recurrence of uveitis, whereas ETA has shown no efficacy in IBD and contradictory results for uveitis33. The gene discussed is TNF; the disease is inflammatory bowel disease.