To investigate the clinical significance of NatD expression inpatients with non-small cell lung cancer (NSCLC), we first examined NatD mRNA levels in human lung cancer tissues.Quantitative real-time PCR analysis showed that 69% (20/29) of lung cancer tissuesamples showed significantly elevated NatDlevels compared to adjacent normal tissue samples (Fig. 1a). This evidence concerns the gene NAA40 and lung cancer.