In contrast, our findings showed maspin expression was inversely linked to depth of invasion, TNM staging and dedifferentiation of gastric cancer regardless of its mRNA and protein, indicating that its hypoexpression was involved in invasion and progression of gastric cancer, in agreement with the reports about breast, prostatic, colonic, bladder, and cervical cancers [15, 27]. This evidence concerns the gene SERPINB5 and cervical cancer.