Actually, IL-17A, which is secreted by Th17, γδ T, Tc17 and mast cells in tumor tissue, could promote cancer-elicited inflammation and prevent tumor cells from immune surveillance [17], through subverting T cell mediated anti-tumor immune responses by polarization of myeloid-derived suppressor cells (MDSCs) [41]. The gene discussed is IL17A; the disease is neoplasm.