The increased levels of TNF-α, IL-12 and IFN-γ and undetectable levels of IL-4 and IL-10 suggest that TME in lacrimal gland B-cell lymphoma was polarized toward Th1 pattern, which is similar to what were previously observed with an intraocular B-lymphoma [8]. Here, IL4 is linked to B-cell non-Hodgkin lymphoma.