HIF1A and neoplasm: This part of study is focused on the expression of genes potentially important for the development of cancer: 1) acquisition of autonomous proliferative signalling (EGFR, EGF); 2) proliferative activity of tumor cells (MKI67); 3) cell cycle and cell death modifications (BCL2, BAX, FOS, JUN, TP53, BIRC5, MAP1LC3B, BECN1, NFKB1, MTOR, CAV1); 4) angiogenesis (VEGF/FLT1); 5) metastatic potential (MMP2); 6) oxidative stress response (MT1A, MT2A, ZIP1, HIF1A), pluripotency genes (NANOG, SOX2, POU5F1); and 7) immune response (CCL2, IL6, IL6R).