It was observed that there was inversed but not significant correlation, which was in agreement with Pfeifer M et al’s report [8] reporting that in GCB DLBCL, the PTEN status was inversely correlated with activation of the PI3K/ AKT pathway in both DLBCL cell lines and primary patient samples. The gene discussed is AKT1; the disease is diffuse large B-cell lymphoma.