For example, signal transducer and activator of transcription 3 (STAT3), a component of the Janus kinase and signal transducer and activator of transcription (JAK/STAT) signal-transducing pathway, is a downstream target of B-cell lymphoma 6 (BCL-6), which has been highly characterized in non-germinal center (GC)-derived DLBCL [6]. The gene discussed is BCL6; the disease is diffuse large B-cell lymphoma.