As another example for metastasis-related chemokine pathways, CXCR2 is an important factor for efficient metastasis in a mouse model of pancreatic ductal adenocarcinoma [8]: CXCR2 inhibition recruits T cells to alter a cancer-associated niche and enhances T cell dependent-suppression on cancer cells [8]. Here, CXCR2 is linked to cancer.