In particular, the two mature sequences of miR483, miR483-5p and miR483-3p, mapping in the second intron of the insulin-like growth factor 2 (IGF2) gene, have proved to be overexpressed both in the primary tumor [9-11] and the bloodstream [12-14], with a diagnostic and prognostic value [12-14]. The gene discussed is IGF2; the disease is neoplasm.