Interestingly, Oncomine boxed plot of SPC24 expression levels between lung adenocarcinoma and normal samples in multiple datasets showed that SPC24 is consistently over-expressed in lung adenocarcinomas (i.e. 1.5-fold or higher) compared with normal tissues (p < 10–6, Figure 1A) [14–17], indicating a positive role of SPC24 in tumorigenesis of human lung cancer. This evidence concerns the gene SPC24 and lung carcinoma.