In light of the discovery, future studies should be directed to (1) interrogate the mechanism by which SPC24 stimulates development of lung cancer; (2) reveal how SPC24 promotes EMT and metastasis; (3) validate SPC24 as a prognostic marker of lung cancer in clinical cohorts; and (4) test if other components of the spindle checkpoint machinery will confer similar functions as what has been observed for SPC24. This evidence concerns the gene SPC24 and lung cancer.