TET2 gene mutations have been found in a variety of bone marrow malignancies, including acute myeloid leukemia, chronic myelomonocyticleukemia, myelodysplastic syndrome, polycythemiavera, primary myelofibrosis, idiopathic thrombocytosis, mastocytosis et al. [14, 15]. The gene discussed is TET2; the disease is acute myeloid leukemia.