TET2 and primary myelofibrosis: TET2 gene mutations have been found in a variety of bone marrow malignancies, including acute myeloid leukemia, chronic myelomonocyticleukemia, myelodysplastic syndrome, polycythemiavera, primary myelofibrosis, idiopathic thrombocytosis, mastocytosis et al. [14, 15].