Specifically, higher HSP10 levels have been detected in different malignancies such as large bowel cancer [13, 28], hepatocellular carcinoma [14], exocervical cancer [17], serous ovarian cancer [18], mantle cell lymphoma [19] and prostate cancer [34], while lower expression levels of this protein have been discovered in bronchial cancer [35]. Here, HSPE1 is linked to colorectal cancer.