SLC12A5 and nervous system disorder: We chose to assay for the canonical KCC2 function of Cl- extrusion, as the loss of Cl- homeostasis and thus synaptic inhibition, is causal for several neurological disorders (Coull et al., 2003; Huberfeld et al., 2007; Tao et al., 2012; Cellot and Cherubini, 2014; Toda et al., 2014; Kahle et al., 2014; Puskarjov et al., 2014; Stödberg et al., 2015; Banerjee et al., 2016; Saitsu et al., 2016; Tang et al., 2016b).