Previously, we have shown that pregnancy anxiety is linked to fetal DNA methylation in the glucocorticoid receptor gene (NR3C1), which is a key player in the hypothalamic-pituitary-adrenal axis, and to DNA methylation of imprinted genes IGF2 and GNASXL important in fetal growth and development [14, 15]. The gene discussed is NR3C1; the disease is pregnancy.