Moreover, the increased level of circulating IGF1 (insulin-like growth factor 1) in AS patients were also significantly blunted by the TAVR procedure, thus suggesting that this reciprocal relationship between miR-1 and FABP3 protein may be tightly controlled by the IGF1/miR-1/FABP3 signaling axis [159]. Here, FABP3 is linked to aortic stenosis.