Contrary to the above, Peters et al. indicate no role of MALAT1 in PO-induced CH, myocardial remodeling and HF in mouse model(TAC- transverse aortic constriction, and angiotensin II-induced CH) of AS despite its reported role in regulation (binding and inhibition) of antihypertrophic miR-133 [106]. The gene discussed is AGT; the disease is aortic stenosis.