Very recently, Cui et al. reported a significant upregulation of DPF3/BAF45C [Double PHD Fingers 3/BRG1-Associated Factor 45C, a histone acetylation and methylation reader of the SWI/SNF (SWItch/Sucrose Non-Fermentable)-like ATP-dependent BAF (BRG/BRM-associated factor) chromatin remodeling complex] and its two individual splice variants DPF3a (BAF45c1) and DPF3b (BAF45c2) in hypertrophic hearts of patients with hypertrophic cardiomyopathy or AS [96]. This evidence concerns the gene DPF3 and aortic stenosis.