Emerging evidence is encouraging that high expression of NEAT1 serves as a convinced poor prognosis in several types of cancers, such as glioma, ovarian cancer, endometrial endometrioid adenocarcinoma, breast cancer, colorectal cancer, bladder cancer, nasopharyngeal carcinoma, gastric cancer, esophageal squamous cell carcinoma, non-small cell lung cancer and so on. Here, NEAT1 is linked to esophageal squamous cell carcinoma.