EZH2 and diffuse large B-cell lymphoma: Chromatin immunoprecipitation (ChIP) experiments confirmed that EZH2 binds to the CDKN1A promoter in primary human GC B cells and diffuse large B cell lymphoma (DLBCL) cell lines, with concordant enrichment of its H3K27me3 repressive mark (Supplementary Fig. 1C, D).