Furthermore, the documented role of TRIB3 as a nexus between diabetes and cancer (Izrailit et al., 2013; Mondal et al., 2016) can inform tests of Trbl in recently developed fly insulin-regulated tumor models (Figueroa-Clarevega and Bilder, 2015; Kwon et al., 2015). This evidence concerns the gene TRIB3 and diabetes mellitus.