FOXP3 and gastric cancer: Using the CD8+T:PD-L1 ratio, we were able to divide the samples into three class groups, and further integrating the CD8+T:Foxp3 ratio, which increased the complicity of immune phenotypes status, we defined 6–7 signatures and allowed the separation of gastric cancer patients at the same stage into different risk-group subsets (Fig. 6).