IL-15 enhanced CD94 expression on NK cells from controls (2949.9±269.7 vs. 1860.8±304.5, p = 0.001), inactive SLE disease (3882.0±413.6 vs. 3507.1±341.8, p = 0.003), and active SLE disease (4921.1±513.3 vs. 4110.1±386.3, p = 0.001), respectively. The gene discussed is KLRD1; the disease is systemic lupus erythematosus.