The level of protection against B. melitensis 16M infection (vaccination effectiveness) in vaccinated sheep (55.6–66.7%) and goats (44.4–55.6%), and their fetuses or lambs (77.8–90.0%)/yeanlings (70–72.7%) was also significant (alpha = 0.04–0.005, excluding goats in the Flu-BA_Omp19-SOD group, 44.4%), when compared with the control sheep and goats groups which had 100% abortion and 83.3–100% of their fetuses or lambs/yeanlings were infected. The gene discussed is SOD1; the disease is infection.