Among the significant network nodes 14/23 were supported by literature to be involved in pancreatic cancer (ELK1, ELK3, NFKB2, MXD1, NCK1, AKT1, YWHAH, STAT5A, TRAF6, MUC1, ZEB1, NFATC2, PRKCZ and SHC1). Here, AKT1 is linked to familial pancreatic carcinoma.