In contrast, only the post-ischemic AF (2.400 ± 0.778), AoP (68.800 ± 3.952) and dp/dt (558.300 ± 55.630) showed significant reduction in MSH treated group compared to pre-ischemic values (AFpre: 22.800 ± 2.480; dp/dtpre: 1133 ± 127.200; AoPpre: 98.200 ± 2.760). The gene discussed is POMC; the disease is atrial fibrillation.