EPHA7 and neoplasm: In addition, they demonstrated that EphA7 negatively regulates neural progenitor cell proliferation in brain development.25, 26 Consistent with the previous studies,12, 25, 26 our study showed that the overexpression of EphA7 also significantly inhibited cell proliferation and induced PCa cell apoptosis in vitro and in vivo, which delayed the primary tumor growth in vivo.