To investigate whether the phosphorylation of EphA7 is correlated to ephrinA5 expression in clinical samples, we first used real-time PCR analysis to examine the mRNA level of EphA7 and its ligand ephrinA5 in 50 benign prostate hyperplasia (BPH) tissues and 64 PCa specimens. This evidence concerns the gene EPHA7 and benign prostatic hyperplasia.