TP53 and colorectal carcinoma: Similar results were observed in p53+/+/p53−/− cells: the viability of p53+/+CRC cell line RKO in the PDT (+)+miR-124 group was the lowest, whereas the viability of p53−/−CRC cell line HT29 in the PDT (−)+miR-SCR group was the highest (Figure 4c).