CDK14 and cancer: CDK14, also called PFTK1 (PFTAIRE protein kinase 1), is highly expressed in breast cancer, oesophageal cancer, lung cancer, liver cancer, gastric cancer, pancreatic cancer and ovarian cancer.41, 42, 43, 44, 45, 46, 47, 48 Although CDK14 has been implicated in cancer development and progression, its essential role in OS oncogenesis and progression remains unknown.