Studies have demonstrated that the lncRNA HULC is associated with the proliferation, invasion, metastasis and survival of tumor cells in certain cancers.17, 18, 19, 20, 21, 22 Furthermore, overexpression of HULC serves as an independent indicator of patient prognosis, by predicting the rates of recurrence and disease-free survival.20 Our results showed that HULC expression was significantly higher in EOC than in benign tumor, and normal ovarian tissues. The gene discussed is HULC; the disease is benign neoplasm.