Moreover, HLA-A*02-01-tetramer staining for epitopes derived from six known T1D autoantigens demonstrated glucose-6-phosphatase 2 (G6Pase 2)-reactive CD8+ T cells to be the most prevalent within lesions examined from 45 T1D donors of varying disease durations [34]. The gene discussed is CD8A; the disease is type 1 diabetes mellitus.