We separately administered peptides 1018 (10 mg/kg) and DJK-5 (3 mg/kg) directly into the abscess 1 h after the infection was initiated, and found that the peptides significantly reduced tissue dermonecrosis by ∼50% for PAO1 (DJK-5 only; although the appearance of 1018-treated lesions indicate less severe lesions) and LESB58 (Figures 4A,C). Here, SMOX is linked to abscess.