NFKB1 and allergic disease: On the other hand, due to KC patients showed more frequent history of allergy disease compared to the control group, we performed a multiple linear regression analysis, adjusted by allergic disease, in order to analyze the independent influence of TLR2/TLR4 expression in monocytes and neutrophils on NF-κB levels, the main proinflammatory factor induced by TLRs.